Purpose: In order to foster students' ability to perform hand washing on their own accord for infection control, this study develops and implements an instructional strategy which arouses students' interest, and examines its effectiveness.Subjects: 92 first year students of A Nursing CollegeMethod: A survey was conducted using a self administered questionnaire before and after the class. Simple tabulation and chi square test were performed on numerical data, while common elements were extracted from free answers. Results: Significant differences were observed in the following items surveyed before and after the class:(1)Two items concerning perception of hand washinginterest in hand hygiene" and interest in hand washing"(p<0.01);(2)Three items concerning nurses' perception of the need for hand washing- after pulse measurement" after touching the uniform" and before entering a ward"(p<0.01); (3)Two items concerning perception of normal hand washing behaviors- palm area" and hand lines" being among the unclean parts of the hand(p<0.01). The level of self learning goal attainment was high at 87.0%, and the education methods that helped students attain their goals were exercises in hand washing and checking for cultivation of bacteria. Matters discovered through the class were classified into eight categories including current state of personal hand washing"and"presence of bacteria in our immediate surroundings." Types and influence of bacteria" and appropriate method of hand washing" were among the eight categories identified as matters the students wanted to learn more about after the class.